There are many reasons why companies choose to locate in this area:

Highest industrial concentration in Mercosul (Common South American Market).
A share in the 100 million consumer market from Mercosul.
Brazil's major export area in cars, auto-parts, steel, mechanical equipment, chemical products and shoes.
Most of the 600 Brazilian companies with the ISO-9,000 quality certificate, located in the Tietê-Paraná River
area.
Most of the multinational companies in Brazil concentrated in this privileged area. Among them:

                    •  Ford
               • Volkswagen 
               • GM
               • Shell
               • BAT
               • Fiat
               • Carrefour
               • Gessy Lever 
               • Esso
               • Texaco
               • Mercedes Benz 
               • *Caterpillar 
               • *Dedini 
               • *Delphi Energy Systems (GM) 
               • *Nabisco 
             

               *Located in Piracicaba